Buffer could limit environmental spread of antibiotic resistance


Scott Schrage, September 7, 2020

Buffer could limit environmental spread of antibiotic resistance

Welcome to Pocket Science: a glimpse at recent research from Husker scientists and engineers. For those who want to quickly learn the “What,” “So what” and “Now what” of Husker research.



Many livestock receive antibiotics that protect against bacterial diseases. But over time, antibiotics also trigger the evolution of bacteria that can resist them. Those antibiotic-resistant bacteria, in turn, can pass along genes responsible for that resistance to other bacterial species, ultimately reducing the effectiveness of the drugs.

When manure from livestock administered with antibiotics is applied as fertilizer, antibiotic resistance genes can enter soil and, following precipitation, run off into rivers and other bodies of water, furthering their spread.

So what?

A research team led by Nebraska’s Xu Li ran experiments to evaluate the minimum distance between a manure slurry-covered field and surface water that would prevent the runoff of antibiotics and antibiotic resistance genes. The team found that levels of all three antibiotics it measured, along with seven of the 10 resistance genes, substantially decreased as that distance increased.

The researchers concluded that maintaining between 112 and 220 feet of distance would limit most runoff pollution across a no-till field rich in the clay soils common to southeastern Nebraska.

Now what?

Because that recommended distance is specific to the experimental site, the team recommended running similar experiments with varying field conditions, soil types, slopes and rainfall amounts to calibrate suitable distances elsewhere.

Agriculture Institute of Agriculture and Natural Resources