Use of genome editing tools requires disclosure

News for Researchers

Posted May 3, 2018 by Ashley Washburn

Genome editing technologies – powerful tools for altering organisms’ DNA – are being utilized in many University of Nebraska-Lincoln research projects. Prior to initiating a project, researchers must register use of these technologies with the Institutional Biosafety Committee.

National Institutes of Health guidelines require scientists to register projects using CRISPR/Cas9; transcription activator-like effector nucleases; and zinc-finger nucleases. Researchers who are using, or intend to use, genome editing technologies but have not identified them in existing registered protocols must file an amendment with IBC.

Failure to register new recombinant nucleic acid research by submitting a protocol or an amendment to IBC may result in non-compliance with NIH guidelines, which the university is required to disclose. IBC protocol forms and amendments may be completed through NUgrant.

For more information about using gene editing technology, contact Matt Anderson, biosafety officer, at 402-472-9554.

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