Genetic Differences in Hemoglobin Function Between Highland and Lowland Deer Mice
On the cover: In natural populations of deer mice (Peromyscus maniculatus), allelic variation in hemoglobin–oxygen affinity plays a key role in physiological adaptation to different elevational zones. In an experimental analysis of oxygen binding properties, Storz et al. (pp. 2565–2574) discovered the specific biochemical mechanisms responsible for differences in hemoglobin function between populations of mice that are native to different altitudes.
Photograph courtesy of Mark Chappell.
Storz, J. F., A. M. Runck, H. Moriyama, R. E. Weber, and A. Fago. August 2010. Genetic differences in hemoglobin function between highland and lowland deer mice. Journal of Experimental Biology 213(15).
Jay Storz is Susan J. Rosowski Associate Professor in the School of Biological Sciences. Hideaki Moriyama is an associate professor in the School of Biological Sciences.